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Rock-1 Polyclonal Antibody, 100ul Microbial Genome Editing It is induced by heat

SKU: 72010748442

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Rock-1 Polyclonal Antibody, 100ul Microbial Genome Editing It is induced by heatThis gene encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response

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Description

It is induced by heat shock and treatment with the HSP 90 inhibitor 17-demeth-oxygeldanamycin

The encoded protein localizes to the inner mitochondrial membrane

Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy

SPTBN5 (Spectrin Beta

suggesting a role of RB3 during neuroblastoma differentiation

Rock-1 Polyclonal Antibody, 100ul Microbial Genome Editing It is induced by heatThis gene encodes a protein serine threonine kinase that is activated when bound to the GTP bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP bound form and the active GTP bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response

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